8 Early Online articles
Special Issue Article “Skin Cancer” | May 31, 2022

Patients’ Perception of Skin Cancer Screening Conducted by Trained and Untrained Doctors: A Controlled and Non-Randomized Intervention Study

Inga-Marie Hübner, Jessica Achter, Elisa Grossmann, Susanne Fengler, Lynne Robertson, Gordon Searles, Mike Kalisiak, Susan Poelman, Kohelia Choudhury, Eckhard Breitbart

Background and Objectives: Due to a lack of evidence regarding patient-reported outcomes in the scope of doctors’ training programs for skin cancer screening, data of the Skin Cancer Screening Education Study (SCSES) are going to be evaluated. The object of research is to analyze differences in the patients’ perception of skin cancer screening between an intervention region with trained doctors and a control regio...

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Cervical Cancer and Disparities | Apr 25, 2022

Cervical Cancer and Disparities: How to Approach the Same Disease in so Many Different Scenarios?

Heinke Thais

Cervical cancer is an important cause of death mostly in low-middle-income countries and consists in a challenge due to the recent WHO initiative to eradicate it as a public health problem worldwide taking into account the different scenarios found among countries, with huge disparities both in incidence and mortality rates

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Actinic keratosis | Mar 09, 2020

Prevention of Actinic Keratosis with Topical Imiquimod 3.75% Cream

Daisy Kopera

Background: Imiquimod 3.75% is licensed in the USA (FDA) and Europe (EMA) for the treatment of actinic keratosis (AK). Objective: This case report shall show that subclinical actinic keratoses can originally be detected by the use of imiquimod cream in uv-exposed areas even if no lesions are clinically present. Material and Methods: A 59-year old female without visible clinical signs of uvdamage like acitinic lent...

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COVID-19 | Nov 03, 2020

Is COVID-19 Dangerous in People with Cancer?

Mahdi Naeim

In some people, coronavirus infection is associated with more severe symptoms and more serious consequences. The following groups experience the most severe symptoms of coronavirus infection:  People over 60 years old  People with underlying diseases such as cardiovascular disease and diabetes  Those whose immune systems are already weak for any reason or who have been suppressed in order to treat other disease...

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Special Issue Article “Lung Cancer” | May 22, 2020

Therapeutic Startegies for Cancer Sub-Types Overexpressing Cps1

Nefertiti Muhammad, Jiyeon Kim

Carbamoyl Phosphate Synthetase 1 (CPS1) catalyzes the first and rate-limiting step of the urea cycle. The urea cycle is normally used for ammonia detoxification, exclusively in liver; however, specific cancer subtypes are dependent on CPS1 for pyrimidine biosynthesis and not for ammonia detoxification. Novel small molecule inhibitors of CPS1 were recently identified and shown to have in vitro efficacy against the...

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Cell Membrane | May 15, 2020

Cell Membrane Nanotubes in Development

Moysés Nussenzveig H

Cell Membrane Nanotubes (CMN) are tubular protrusions of the cell membrane that allow it to communicate with distant cells. CMN are employed in cell invasion by practically all pathogens, suggesting that they are of ancient origin. They also play a role in cancer propagation, with possible therapeutic implications. Recent work has shown that they can establish an analogue of a synaptic connection. I have proposed...

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Special Issue Article “Mesothelioma” | Feb 03, 2020

A Struggle against Mesothelioma: Mini Review on the Current Role of Surgery in the Management of Mesothelioma

Tanya Sinha, Azar Hussain, Mahmoud Loubani, Michael Cowen, Syed Qadri

Malignant Pleural Mesothelioma (MPM) is a rare cancer of the pleural surface usually associated with previous asbestos exposure. It often presents with shortness of breath, pleural effusion, weight loss and progressive chest pain. There exists a long latency period between the exposure of asbestos and the development of the pleural mesothelioma, which frequently leads to metastases of the cancer by the time of dia...

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Carcinogenic Endocrine | Jul 20, 2017

Prevention from the Pollution of Carcinogenic Endocrine Disrupting Chemicals in Water Sources

Wei Zhang, Qing Xiu Liu, Jun Sheng Lin

Endocrine Disrupting Chemicals (EDCs) are exogenous chemicals in our environment that interfere with any aspect of hormone action causing a variety of disorders even increasing incidence rate of hormone-sensitive cancers. This mini review mainly focuses on the recent studies on the carcinogenesis of EDCs and the ideas how to reduce EDCs pollution in the aquatic environment. Advanced technologies for sensitive dete...

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